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RENAL NAD(P)H OXIDASE
Descriptors Found:
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DeCS
Descriptor
English
:
NADPH Oxidase 4
Descriptor
Spanish
:
NADPH Oxidasa 4
Descriptor
Portuguese
:
NADPH Oxidase 4
Synonyms
English
:
Nox4 Protein
Renal NAD(P)H Oxidase
Renox NAD(P)H Oxidase
Oxidase 4, NADPH
Tree Number:
D08.811.682.608.575.937
D12.776.331.894.937
D12.776.543.653.937
Definition
English
:
An NADPH oxidase that is strongly expressed in the
kidney
. It forms a complex with CYBA-P22PHOX and produces intracellular
SUPEROXIDES
that may regulate cellular signaling in
APOPTOSIS
;
BONE RESORPTION
; and
NF-KAPPA B
activation.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57025
Unique Identifier:
D000074663
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS